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Wednesday, August 24, 2005

Cancer rates higher near Endicott spill

Study: Spike in kidney, testicular malignancies

BY TOM WILBER
Press & Sun-Bulletin
Find similar archived stories..

ENDICOTT -- George Kretzmer was not surprised Tuesday evening when he learned that he and others living south of the former IBM plant had significantly elevated rates of birth defects and two types of cancers.


 
Q & A About the Findings
Q: Am I in danger of getting cancer if I live in the study area?

A: The state study looks at what happened in the past, but is not a useful tool to predict the future. IBM has installed ventilation systems to divert trichloroethylene gases from more than 430 properties. Tests are ongoing to see whether the pollution in the ground is affecting outside air.

Q: Is the report saying the pollution caused these cases of cancer?

A: No.

Q: Could the cancer have come from other sources?

A: Lifestyle, family history and occupational exposure to chemicals must be taken into consideration. That may be the job of future studies.

Q: What else causes these types of cancers?

A: Many types of cancer have known or suspected risk factors. Smoking can cause kidney cancer.

Q: How can I find out if I am at risk of the cancers in the report?

A: People who smoke and have a family history of cancer have relatively high risk. Chronic exposure to TCE, radon and other agents known to increase cancer risks also are factors that should be considered. If you have any questions about your chances of developing cancer, see your doctor.

Q. When will there be another public meeting on the subject?

A: From noon to 3, and 5 to 8 p.m. today at Union-Endicott High School, Endicott. Scientists will hold one-on-one discussions.

Q: Where can I learn more about the pollution in Endicott, and the investigations related to it?

A: Read dozens of stories, see the cleanup plan and view a map of the affected area at http://www.pressconnects.com/special/endicottspill/

SOURCES: National Cancer Institute, Press & Sun-Bulletin research

"It's hard for me to believe how many people I have buried that are less than 50 years old," Kretzmer told officials from the state Department of Health after they presented the information to residents at a meeting at Union-Endicott High School. "I see a bigger common denominator than I think you're letting on. I don't have a whole bunch of statistics or registry, but this is what I've seen with my own eyes."

The study included an area of about 300 acres polluted by solvents first discovered seeping from the IBM plant on North Street in 1979. It also included several blocks west of Jefferson Avenue, polluted by an undetermined source.

It concluded that people living near the polluted area have higher rates of birth defects, testicular cancer and kidney cancer than would be expected. The study was undertaken after residents learned they had been exposed to low levels of industrial solvents pushing into basements through a process called vapor intrusion. The study takes into account 22 types of cancers from 1980 to 2001. It concludes that elevated rates of testicular and kidney cancers during that time are "unlikely due to chance alone."

But it does not explain what caused them.

"Before any conclusion can be drawn, the issue requires further study," said Robert Kenny, a spokesman for the Department of Health.

Testicular cancer is rare. Statistically, scientists would expect to find 2.2 cases in the study area in 21 years. Six were documented. Cancer of the kidney and renal pelvis is also relatively rare. Scientists found 15 cases in the study area, where fewer than eight were expected.

While the number of testicular and kidney cancers are low compared to more common types of cancer, they are important because they are unusual. In scientific terms, they represent statistical "outliers" that alert scientists to the possibility of a larger problem.

The study also found that heart defects were "significantly higher than expected" for children born in the study area between 1983 and 2000, as were low birth weights for children born between 1978 and 2002.

About 60 people attended the 90-minute meeting. DOH research scientists Steven Forand and Karolina Schabses gave an overview of the study's methodology and findings.

The study has several limitations, Forand told the gathering. It does not account for long-time residents who may have been exposed to the chemicals but moved from the area before they developed an illness. Conversely, it may include new residents who developed an illness soon after moving to the neighborhood, although they may not have been exposed to the chemicals for any significant length of time.

Dave Bohrer, a 50-year-old former Endicott resident and testicular-cancer survivor, is an example of someone who may have been left out.

He lived on Tracy Street, in the polluted area, from 1981 to 1990. He was diagnosed with testicular cancer in 1997, after he had moved to Apalachin. Otherwise, he might have been case number seven.

The cancer was still in its early stages, which greatly increased Bohrer's chances of survival. But it was a shock, said Bohrer, the assistant managing editor of the Ithaca Journal and former assistant sports editor of the Press & Sun-Bulletin.

"You suddenly think about your mortality, about your family and the things you could miss," said Bohrer. He is now cancer-free.

IBM Corp. spokesman Todd Martin pointed out that the study did not determine a cause for the cancers, and that many factors can influence cancer rates.

He also noted that some of the cancers were in the section west of the IBM pollution.

"We've all had a friend or family member diagnosed with one form or another of this disease, and we're cognizant of that," he said.

The area studied is polluted with trichloroethylene (TCE), a solvent once used in the circuit board assembly process, and similar solvents. Scientists discovered in 2003 that the chemical was entering hundreds of basements as vapors.

IBM has installed systems to divert the chemicals from more than 430 properties.

TCE is listed as a "probable human carcinogen" by the federal Environmental Protection Agency. A proposed revision of the EPA guideline, now under review, lists TCE exposure as "highly likely to produce cancer in humans." It documents an association of TCE exposure with increased human kidney cancer and testicular cancer in rats.

But there is little scientific consensus about how much a person has to ingest, or for how long, before it is hazardous.

Other factors, such as diet, smoking and occupational exposure to chemical hazards can also influence cancer rates.

Health officials will review individual case records of kidney and testicular cancers, heart defects and low birth weights to assess any contributing factors, and see whether additional study could determine a cause, according to an overview of the evaluation.

Dr. Joseph Readling, an oncologist who is a partner in Broome Oncology, said there is evidence that suggests exposure to toxic chemicals can increase certain types of kidney cancers. The "jury is still out" as to whether TCE exposure is a factor in the illnesses, he said.

But the study, he added, is important.

"Whether people can get significant exposure to the stuff wafting out of the ground -- I don't think anybody knows that," he said. "This is sort of a first step in trying to get an idea whether there is a connection that is significant."

For Kretzmer, who grew up on Endicott's Lincoln Avenue, there is no question that the pollution caused the illnesses.

"I grew up around this," he said. "It was on my playground and my paper routes. I remember seeing big ponds of liquid stuff that wasn't water."

As he spoke at the meeting, he waved a stack of newspaper obituaries. Kretzmer was diagnosed with Burkitt's lymphoma in 1982 at age 20.

Kretzmer said his condition has left him uninsurable and unable to work for the better part of two decades. Kretzmer also spoke to the DOH about the number of friends he has buried young -- something he has a hard time accepting as coincidence.

But Readling said it may take years of more study to find answers. And that may extend beyond the resources of the Department of Health.

Cancer-incidence studies are not unusual, but finding statistically elevated rates for particular cancers is.

The state has conducted 19 similar studies in communities throughout the state since 2001. None found any elevated rates of testicular cancer. Two found significantly high rates of kidney cancer.

Reporter SCOTT ROCKEFELLER contributed to this story.

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